Research Projects

Research Projects

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A Conversation on Supporting Employees Who Acquire Disabilities Webinar

A panelist shares his own experience of working before and after acquiring a disability including his perspectives on how to successfully navigate corporate policies and practices. Panelists share resources and information on how to successfully support return to work on job retention for individuals with disabilities.

Research Project

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Breathing Low Oxygen to Enhance Spinal Stimulation Training and Functional Recovery in Persons with Chronic Spinal Cord Injury: The BO2ST Trial

The goal of this double-blind, placebo-controlled, block-randomized clinical trial is to investigate the efficacy and potency of daily acute intermittent hypoxia (AIH) combined with transcutaneous electrical spinal stimulation (tSTIM) and skill-based walking practice.

Research Project

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Assessment of a Microprocessor Ankle for Low Mobility Individuals with Amputation: Phase I

This study is being done to conduct a preliminary investigation into a new prosthetic microprocessor controlled ankle, called the Damping, Stiffness, and Repositioning (DSR) ankle. Participants will visit the Shirley Ryan AbilityLab 10-16 times over 9 weeks, each visit lasting approximately 3 hours, to perform a series of walking and mobility tests with both their own prosthetic ankle and the DSR ankle.

Research Project

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COMPLETE: Power Forward Study: A Cross-Sector, Multisite Clinical Trial of a Powered Knee-Ankle-Foot Orthosis

The overall objective of this study is to evaluate the impact of using the Nomad P-KAFO in people who have had a musculoskeletal or neurological injury that has affected their ability to walk.

Research Project

Conceptual framework for considering the status of lower motor neuron degeneration affecting key arm muscles that may be re-animated after spinal cord injury via nerve transfer surgery. In scenario C, which affects 30-40% of patients we screen, nerve transfer surgery should be avoided outside of the first 6 months post-injury due to detrimental impact of chronic muscle denervation on recipient muscle targets. However, reconstruction by tendon transfer may be considered.

Reconstructive Surgery for People with Spinal Cord Injury

The Journal of Neurophysiology recently published a review by Adenike Adewuyi, MD PhD — a 2022 graduate of Shirley Ryan AbilityLab’s physical medicine and rehabilitation (PM&R) residency program — and her mentor, Colin Franz, MD, PhD, physician-scientist, at Shirley Ryan AbilityLab. The review defines a clinical framework for evaluating patients with spinal cord injuries to determine their candidacy for nerve transfer surgery.

Research Project

COVID-19

Preventing Nerve Injuries Acquired in the ICU by Patients with Severe COVID

A new study published in the October 2022 issue of the Journal of NeuroEngineering and Rehabilitation from a research team led by SRAlab clinicians identified the cause of — and hope for a potential prevention of — nerve injuries in patients treated in the intensive care unit for severe COVID-19.

Research Project

Scientific Advances

Tiny Machine Poised to Unlock Brain’s Mysteries

A team of scientists, led by researchers at Shirley Ryan AbilityLab, Northwestern University and the University of Illinois at Chicago, has developed novel technology promising to increase understanding of how brains develop, and offer answers on repairing brains in the wake of neurotrauma and neurodegenerative diseases.

Research Project

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Assessing Feasibility, Efficacy, and Acceptability of Visual Feedback during Heart Rate Monitoring in Rehabilitation

We are interested in monitoring patients' heart rates during group and individual rehabilitation sessions that focus on improving endurance.

Research Project

Survey that reads, "On a scale from 1 to 5, how would you rate..."

Exercise and Physical Activity Surveys: Measurement Validation

In this study, we are looking to validate exercise and physical activity questionnaires compared to an activity monitor.

Research Project

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COMPLETE: Safety, Reliability, and Efficacy of the Harmony SHR Upper Extremity Robotic Rehabilitation System in the Inpatient Rehabilitation Setting for Patients with Acute Stroke

The objective of this study is to evaluate the safety, reliability, and effectiveness of the use of Harmony SHR in rehabilitation of the upper extremities in the inpatient stroke population as compared to conventional occupational therapy.

Research Project