Patient and Speech Language Therapist work on Aphasia therapy

Aphasia Trajectory Research Study

Posted By Lori Snyder

Contact:

Mallory Ward

Join the Clinical Trial:

Trajectory of Recovery in Aphasia

Defining Trajectories of Linguistic, Cognitive-Communication and Quality of Life Outcomes in Aphasia

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About this Research Study

Stroke imposes significant burdens on the health and quality of life of survivors and their caregivers and presents a major public health issue in terms of healthcare costs and lost productivity. Aphasia adds to the cost of stroke-related care.

Many stroke survivors with aphasia receive therapy in inpatient rehabilitation facilities. However, aphasia recovery is variable and there is limited evidence on how inpatient rehabilitation and other forms of treatment contribute to the outcomes of patients. This study aims to describe the trajectories of linguistic, cognitive-communicative, and health-related quality of life outcomes following stroke aphasia.

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aphasia therapy

This study has three objectives

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  1.  Establish a prospective cohort of stroke patients with aphasia, and define their typical trajectory of linguistic, cognitive-communicative, and health-related quality of life recovery at admission to and discharge from the inpatient rehabilitation facility, and at 6, 12, and 18 months after stroke.

  2. Identify factors that are associated with linguistic, cognitive-communicative, and health-related quality of life outcomes from among the following: patient factors including demographic and clinical characteristics related to stroke and aphasia; treatment variables including inpatient and outpatient aphasia therapy characteristics and informal aphasia services; and biomarkers, including genetic and neuroimaging biomarkers.

  3. Evaluate the stability of the models of linguistic, cognitive-communicative, and health-related quality of life outcomes recovery

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Our Mission

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A sample of 300 newly-admitted stroke patients with aphasia recruited at three Midwestern rehabilitation hospitals will complete measures of linguistic and cognitive-communicative performance and quality of life measures during inpatient rehabilitation and at 6-, 12-, and 18- months after stroke. We will model outcomes as individual and group trajectories, allowing us to develop individual predictions that could inform clinical planning and decision-making for future patients.

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Lab News

Our Team

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Shirley Ryan AbilityLab

 

Role

Allen Heinemann

Co-PI

Leora Cherney

Co-PI

Andrea Domenighetti

Genetics

Marwan Baliki

Neuroimaging

Mary Kwasny

Biostatestitian

Linda Lovell

Research Administrator

Mallory Ward

Project Manager

Rosalind Hurwitz

SLP

Kate Spittle

Research Assistant

Kayla Jones

Research Coordinator

 

Alexian/ AMITA staff

 

Linda Foster

Co-I

 

MFB Staff

 

Al Kozlowski

Co-I

Kelsey Boersma

Research Coordinator

Melissa Hoffmann

SLP

Naxal Shah

Research Assistant

Ariel Lugo

Research Assistant

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