Regenerative Neurorehabilitation Laboratory
Colin K. Franz, MD/PhD, Director
Peripheral Nerve Injury and COVID-19
Our lab has seen a number of patients in rehabilitation recovery settings subsequently diagnosed with acquired peripheral nerve injury (PNI) and previously in long-term COVID-19 care in prone position.
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Our Projects
Take a look at a few of the projects we work on everyday.
Reconstructive Surgery for People with Spinal Cord Injury
Research Project
Selected Publications
The Impact of Brain-Derived Neurotrophic Factor rs6265 (Val66Met) Polymorphism on Therapeutic Electrical Stimulation for Peripheral Nerve Regeneration: A Preclinical Study of Therapy-Genotype Interactions.
INTRODUCTION/AIMS: Therapeutic electrical stimulation (TES) shows promise in enhancing nerve regeneration, but outcomes vary widely. This study investigates the impact of the rs6265 single nucleotide polymorphism (SNP) on TES efficacy in a preclinical rat model and human stem cell-derived motor neurons. METHODS: Wild-type (WT) and rs6265 variant rats underwent sciatic nerve transection and received either TES or sham treatment. Muscle reinnervation was assessed through compound muscle action…
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