• Welcome to the Biologics Lab

    Explore what translational biomedical research is about at Shirley Ryan AbilityLab.
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    A Minimally Invasive Tool to Measure Muscle Impairment

    A minimally invasive technique that measures the contraction of living muscle tissue could be an alternative to the painful muscle biopsies.
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    Stem-Cell Breakthroughs Promise Novel Treatments for Cerebral Palsy and Related Conditions

    Although the cause of CP is a mystery, researchers at RIC are at the forefront to understand, treat, and ultimately cure, this life-long neurological disorder.
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    Our Projects

    Take a look at a few of the projects we work on everyday.

    Muscle Impairment in Children with Cerebral Palsy: a Role for Muscle Stem Cell Dysfunction and Drug Repurposing
    PROJECT TYPE: Cerebral Palsy, Muscle, Biology, Muscle Fibers, Cell Biology, Stem Cells, Cell Culture

    Research Project

    Defining trajectories of linguistic, cognitive-communicative and quality of life outcomes in aphasia
    PROJECT TYPE: Stroke, Aphasia, Quality Improvement, Outcomes, Brain, Biology, Speech Disorders

    Research Project

    Pressure and Muscle Force
    PROJECT TYPE: Muscle

    Research Project

    Sarcomere Measurements
    PROJECT TYPE: Muscle Fibers, Muscle, Cerebral Palsy, Muscular Dystrophy, Physiology

    Research Project

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    Clinical Trials

    Please join our research in progress by considering becoming a participant.

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    The acute impact of lower body positive pressure treadmill walking on biological markers of joint disease in individuals with knee pathology

    The purpose of this trial is to determine the impact of dynamic offloading on the biological composition of the knee joint in individuals with knee osteoarthritis.

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    The relationship between lower extremity pain, function and biomarkers of osteoarthritis in adolescents and young adults with cerebral palsy

    The purpose of this trial is to identify novel biomarkers associated with the response of cartilage to joint stress

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    The acute impact of lower body positive pressure treadmill walking on biological markers of joint disease in individuals with knee pathology

    The purpose of this trial is to determine the impact of dynamic offloading on the biological composition of the knee joint in individuals with knee osteoarthritis.

    read more

    Selected Publications

    Altered functional connectivity associated with time discounting in chronic pain.

    Chronic pain (CP) is a global problem extensively associated with an unhealthy lifestyle. Time discounting (TD), a tendency to assign less value to future gains than to present gains, is an indicator of the unhealthy behaviors. While, recent neuroimaging studies implied overlapping neuro mechanisms underlying CP and TD, little is known about the specific relationship between CP and TD in behavior or neuroscience. As such, we investigated the association of TD with behavioral measures in CP and…

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    Interested in joining us?

    Contact Our Lab