Biologics Lab: Publications

Human spinal cord organoids: A powerful tool to redefine gray matter and lower motor neuron pathophysiology in spinal cord injury.

Quezada MJ, Franz CK
Neural regeneration research

Double Supinator Branch Transfer to Posterior Interosseous Nerve May Confer Superior Hand Opening Restoration Outcomes in Brachial Plexus and Spinal Cord Injury Compared to Single Branch.

Texakalidis P, Murthy N, Franz CK, Swong K
Operative neurosurgery (Hagerstown, Md.)

Macrophages, muscle stem cells, and repair; immunohistochemical characteristics in muscle growth impairments in children with cerebral palsy.

Meza G, Kahn RE, Patel NM, Larson JE, Swaroop VT, Dayanidhi S
American journal of physiology. Cell physiology

Does Time Tick Faster in Cerebral Palsy? Accelerated Aging as a Framework for Skeletal Muscle Dysfunction.

Horwath O, Edman S, Dayanidhi S, Englund D, Peterson MD, von Walden F
FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Ultrasound-guided skeletal muscle biopsy technique permits measurement of structural, functional, cellular and biochemical properties.

Barber A, Willbanks A, Meza G, Ferey JLA, Meyer GA, Dayanidhi S, Arnold WD, Lieber RL, Roy I
Scientific reports

Microscopic and molecular aspects of skeletal muscle alterations in cerebral palsy.

Edman S, Horwath O, Pontén E, Dayanidhi S, von Walden F
Developmental medicine and child neurology

Secretome Profiling of Young Multipotent Stem Cells Reveals Angiogenic and Immunomodulatory Mechanisms Supporting Aged Neuromuscular Health.

Thompson SD, Rugel CL, Haller MR, Curtin JL, Dayanidhi S, Lavasani M
Aging cell

Elastic and viscoelastic properties of human cortical organoids.

Samei Y, Cheung I, Papavasileiou P, Franz CK, Finan JD
Acta biomaterialia

Time-of-day effects on muscle mitochondria following short-term ablation of satellite cells.

Kahn RE, Dinnunhan F, Meza G, Lieber RL, Lacham-Kaplan O, Hawley JA, Dayanidhi S
Frontiers in physiology

The Impact of Brain-Derived Neurotrophic Factor rs6265 (Val66Met) Polymorphism on Therapeutic Electrical Stimulation for Peripheral Nerve Regeneration: A Preclinical Study of Therapy-Genotype Interactions.

Walters JB, Quezada MJ, He S, Haynes CS, Steece-Collier K, Collier TJ, Sortwell CE, Franz CK
Muscle & nerve

Multipoint Stimulation Motor Unit Number Estimation of the Extensor Indicis and Anconeus After Spinal Cord Injury.

Adewuyi AA, Hashemi M, Khanna S, Berger MJ, Franz CK
Muscle & nerve

Applications of advances in therapeutic electrical stimulation techniques and technologies in precision peripheral nerve repair: a narrative review.

Kennedy V Jr, Long MD, Walters J, Adewuyi AA, Franz CK
Advanced technology in neuroscience

Bioresorbable, wireless dual stimulator for peripheral nerve regeneration.

Ahn HY, Walters JB, Avila R, Oh S, Seo SG, Kim JU, Park J, Yoo S, Choi YS, Kim TY, Liu J, Yoo JY, Weissleder OR, D'Andrea D, Park C, Lee G, Cho D, Maeng WY, Yoon HJ, Wickerson G, Bouricha Y, Tian J, Chung TC, Jordan SW, Li S, Huang Y, Franz CK, Rogers JA
Nature communications

Serum metabolomics after exercise in ambulatory individuals with cerebral palsy.

Hanaoka C, Pichika R, Dayanidhi S, Jayabalan P
Developmental medicine and child neurology

Stress and stiffness as predictors of shear wave velocity in peripheral nerve.

Rugel CL, Thompson SD, Franz CK, Heckman CJ, Lavasani M, Lee SSM
PloS one

Nerve transfers to anterior interosseous nerve for restoration of finger flexion in spinal cord and brachial plexus injury: a systematic Review and individual-patient-data meta-analysis.

Texakalidis P, Matsoukas S, Murthy N, Adewuyi AA, Dahdaleh NS, Franz CK, Swong K
Spinal cord

Anomalous education: You can't bypass electrodiagnostic training in PM&R residency.

Howard IM, Tan FC, Irwin RW, Laughlin RS, Chiodo A, Grant PA, Adkins S, Krzesniak-Swinarska M, Malhotra G, Franz CK, Quan D
PM & R : the journal of injury, function, and rehabilitation

Ablation of satellite cell-specific clock gene, Bmal1, alters force production, muscle damage, and repair following contractile-induced injury.

Kahn RE, Zhu P, Roy I, Peek C, Hawley JA, Dayanidhi S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology

The ankle-brachial index, gastrocnemius mitochondrial respirometry, and walking performance in people with and without peripheral artery disease.

McDermott MM, Dayanidhi S, Leeuwenburgh C, Wohlgemuth SE, Ferrucci L, Peterson CA, Tian L, Sufit R, Zhao L, Slysz J, Polonsky TS, Guralnik JM, Kibbe MR, Ho KJ, Criqui MH, Zhang D, Xu S, Greenland P
Vascular medicine (London, England)

Extracting high-quality RNA from formaldehyde-fixed naturally aged neuromusculoskeletal tissues.

Thompson SD, Pichika R, Lieber RL, Lavasani M
BioTechniques

Sex-specific preservation of neuromuscular function and metabolism following systemic transplantation of multipotent adult stem cells in a murine model of progeria.

Thompson SD, Barrett KL, Rugel CL, Redmond R, Rudofski A, Kurian J, Curtin JL, Dayanidhi S, Lavasani M
GeroScience

Relationship Between Cachexia and the Functional Progress of Patients With Cancer in Inpatient Rehabilitation.

Roy I, Huang K, Bhakta A, Marquez E, Spangenberg J, Jayabalan P
American journal of physical medicine & rehabilitation

Factors associated with unplanned transfers among cancer patients at a freestanding acute rehabilitation facility.

Bhakta A, Roy I, Huang K, Spangenberg J, Jayabalan P
PM & R : the journal of injury, function, and rehabilitation

Teamwork Pays! Ten Tips for a Great Surgeon-Scientist Collaboration.

Lieber RL, Fridén J
The Journal of hand surgery

Effects of voluntary exercise on muscle structure and function in cerebral palsy.

Moreau NG, Lieber RL
Developmental medicine and child neurology

Assessment of Cancer-Associated Cachexia - How to Approach Physical Function Evaluation.

Fram J, Vail C, Roy I
Current oncology reports

An estrogen-sensitive fibroblast population drives abdominal muscle fibrosis in an inguinal hernia mouse model.

Potluri T, Taylor MJ, Stulberg JJ, Lieber RL, Zhao H, Bulun SE
JCI insight

Procedures for obtaining muscle physiology parameters during a gracilis free-functioning muscle transfer in adult patients with brachial plexus injury.

Persad LS, Ates F, Evertz LQ, Litchy WJ, Lieber RL, Kaufman KR, Shin AY
Scientific reports

Cachexia is a risk factor for negative clinical and functional outcomes in patients receiving chimeric antigen receptor T-cell therapy for B-cell non-Hodgkin lymphoma.

Roy I, Smilnak G, Burkart M, Hamilton E, Thorp K, Miyata S, Ma S, Pro B, Winter J, Gordon L, Karmali R
British journal of haematology

A systematic review of pharmacologic treatment efficacy for depression in older patients with cancer.

Rabin EE, Kim M, Mozny A, Cardoza K, Bell AC, Zhai L, Bommi P, Lauing KL, King AL, Armstrong TS, Walunas TL, Fang D, Roy I, Peipert JD, Sieg E, Mi X, Amidei C, Lukas RV, Wainwright DA
Brain, behavior, & immunity - health

Can we just forget about pennation angle?

Lieber RL
Journal of biomechanics

Starting at Birth: An Integrative, State-of-the-Science Framework for Optimizing Infant Neuromotor Health.

Peyton C, Sukal Moulton T, Carroll AJ, Anderson E, Brozek A, Davis MM, Horowitz J, Jayaraman A, O'Brien M, Patrick C, Pouppirt N, Villamar J, Xu S, Lieber RL, Wakschlag LS, Krogh-Jespersen S
Frontiers in pediatrics

Systematic review of skeletal muscle passive mechanics experimental methodology.

Binder-Markey BI, Sychowski D, Lieber RL
Journal of biomechanics

Miniaturized wireless, skin-integrated sensor networks for quantifying full-body movement behaviors and vital signs in infants.

Jeong H, Kwak SS, Sohn S, Lee JY, Lee YJ, O'Brien MK, Park Y, Avila R, Kim JT, Yoo JY, Irie M, Jang H, Ouyang W, Shawen N, Kang YJ, Kim SS, Tzavelis A, Lee K, Andersen RA, Huang Y, Jayaraman A, Davis MM, Shanley T, Wakschlag LS, Krogh-Jespersen S, Xu S, Ryan SW, Lieber RL, Rogers JA
Proceedings of the National Academy of Sciences of the United States of America

Differential DNA methylation and transcriptional signatures characterize impairment of muscle stem cells in pediatric human muscle contractures after brain injury.

Sibley LA, Broda N, Gross WR, Menezes AF, Embry RB, Swaroop VT, Chambers HG, Schipma MJ, Lieber RL, Domenighetti AA
FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Skeletal muscle maximal mitochondrial activity in ambulatory children with cerebral palsy.

Dayanidhi S, Buckner EH, Redmond RS, Chambers HG, Schenk S, Lieber RL
Developmental medicine and child neurology

Differential DNA methylation and transcriptional signatures characterize impairment of muscle stem cells in pediatric human muscle contractures after brain injury.

Sibley LA, Broda N, Gross WR, Menezes AF, Embry RB, Swaroop VT, Chambers HG, Schipma MJ, Lieber RL, Domenighetti AA
FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Systemic transplantation of adult multipotent stem cells prevents articular cartilage degeneration in a mouse model of accelerated ageing.

Thompson SD, Pichika R, Lieber RL, Lavasani M
Immunity & ageing : I & A

Systemic Transplantation of Adult Multipotent Stem Cells Functionally Rejuvenates Aged Articular Cartilage.

Thompson SD, Pichika R, Lieber RL, Budinger GRS, Lavasani M
Aging and disease

Mesenchymal stem cell-derived extracellular vesicles reduce senescence and extend health span in mouse models of aging.

Dorronsoro A, Santiago FE, Grassi D, Zhang T, Lai RC, McGowan SJ, Angelini L, Lavasani M, Corbo L, Lu A, Brooks RW, Garcia-Contreras M, Stolz DB, Amelio A, Boregowda SV, Fallahi M, Reich A, Ricordi C, Phinney DG, Huard J, Lim SK, Niedernhofer LJ, Robbins PD
Aging cell

Commentary: Muscle Microbiopsy to Delineate Stem Cell Involvement in Young Patients: A Novel Approach for Children With Cerebral Palsy.

Lieber RL, Domenighetti AA
Frontiers in physiology

Ultrasonographic comparison of the lateral epicondyle in wheelchair-user (and able-bodied) tennis players: A pilot study.

Roy V, Lee L, Uihlein M, Roy I, Lee K
The journal of spinal cord medicine

Conference report on contractures in musculoskeletal and neurological conditions.

Nuckolls GH, Kinnett K, Dayanidhi S, Domenighetti AA, Duong T, Hathout Y, Lawlor MW, Lee SSM, Magnusson SP, McDonald CM, McNally EM, Miller NF, Olwin BB, Raghavan P, Roberts TJ, Rutkove SB, Sarwark JF, Senesac CR, Vogel LF, Walter GA, Willcocks RJ, Rymer WZ, Lieber RL
Muscle & nerve

Building a Professional Identity and an Academic Career Track in Translational Medicine.

van Dijk SJ, Domenighetti AA, Gomez-Ospina N, Hunter P, Lindemans CA, Melotte V, van Rossum AMC, Rosenblum ND
Frontiers in medicine

Altered functional connectivity associated with time discounting in chronic pain.

Wakaizumi K, Jabakhanji R, Ihara N, Kosugi S, Terasawa Y, Morisaki H, Ogaki M, Baliki MN
Scientific reports

Muscle contracture and passive mechanics in cerebral palsy.

Lieber RL, Fridén J
Journal of applied physiology (Bethesda, Md. : 1985)

Deconstructing biomarkers for chronic pain: context- and hypothesis-dependent biomarker types in relation to chronic pain.

Reckziegel D, Vachon-Presseau E, Petre B, Schnitzer TJ, Baliki MN, Apkarian AV
Pain

Reach out and grasp the opportunity: reconstructive hand surgery in tetraplegia.

Fridén J, Lieber RL
Journal of Hand Surgery (European Volume)

A Stimulus-Response Framework to Investigate the Influence of Continuous Versus Interval Walking Exercise on Select Serum Biomarkers in Knee Osteoarthritis.

Jayabalan P, Gustafson J, Sowa GA, Piva SR, Farrokhi S
American journal of physical medicine & rehabilitation

Physical Activity and Worsening of Radiographic Findings in Persons With or at Higher Risk of Knee Osteoarthritis.

Jayabalan P, Kocherginsky M, Chang AH, Rouleau GW, Koloms KL, Lee J, Dunlop D, Chang RW, Sharma L
Arthritis care & research

Inferring distinct mechanisms in the absence of subjective differences: Placebo and centrally acting analgesic underlie unique brain adaptations.

Tétreault P, Baliki MN, Baria AT, Bauer WR, Schnitzer TJ, Apkarian AV
Human brain mapping

Loss of myogenic potential and fusion capacity of muscle stem cells isolated from contractured muscle in children with cerebral palsy.

Domenighetti AA, Mathewson MA, Pichika R, Sibley LA, Zhao L, Chambers HG, Lieber RL
American journal of physiology. Cell physiology

Acute management of cervical spine trauma.

Dadabo J, Jayabalan P
Sports Neurology

Management of Cardiac Involvement Associated With Neuromuscular Diseases: A Scientific Statement From the American Heart Association.

Feingold B, Mahle WT, Auerbach S, Clemens P, Domenighetti AA, Jefferies JL, Judge DP, Lal AK, Markham LW, Parks WJ, Tsuda T, Wang PJ, Yoo SJ, American Heart Association Pediatric Heart Failure Committee of the Council on Cardiovascular Disease in the Young; Council on Clinical Cardiology; Council on Cardiovascular Radiology and Intervention; Council on Functional Genomics and Translational Biology; and Stroke Council
Circulation

mTOR signaling plays a critical role in the defects observed in muscle-derived stem/progenitor cells isolated from a murine model of accelerated aging.

Takayama K, Kawakami Y, Lavasani M, Mu X, Cummins JH, Yurube T, Kuroda R, Kurosaka M, Fu FH, Robbins PD, Niedernhofer LJ, Huard J
Journal of orthopaedic research : official publication of the Orthopaedic Research Society

Cullin E3 Ligase Activity Is Required for Myoblast Differentiation.

Blondelle J, Shapiro P, Domenighetti AA, Lange S
Journal of molecular biology

Structural basis for chemokine recognition by a G protein-coupled receptor and implications for receptor activation.

Ziarek JJ, Kleist AB, London N, Raveh B, Montpas N, Bonneterre J, St-Onge G, DiCosmo-Ponticello CJ, Koplinski CA, Roy I, Stephens B, Thelen S, Veldkamp CT, Coffman FD, Cohen MC, Dwinell MB, Thelen M, Peterson FC, Heveker N, Volkman BF
Science signaling

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