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Evaluating the Use of Acute Intermittent Hypoxia to Improve Symptoms in Persons with Multiple Sclerosis

Posted By Yashna Singh

PI: Milap Sandhu, PT, Phd.


This study better understands a treatment that may help improve mobility in individuals with Multiple Sclerosis (MS). In some people with neurological problems that cause mobility difficulties (similar to those of people with MS), a new type of treatment has been studied to improve their muscle strength and control. 
This treatment, called acute intermittent hypoxia (AIH), has been successful in improving motor function, without any side effects. But, to date, AIH has not been studied in people with MS. The goal of this project is to study if and how AIH therapy would work in people with relapsing-remitting MS. For this study, we want to evaluate muscle control and strength in the lower limbs and whether AIH results in improvements. The logic behind AIH is that changing oxygen content as you breath (like breathing in high altitudes) may enhance muscle strength.

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