Midwest Regional Spinal Cord Injury Care System (MRSCICS)

Midwest Regional Spinal Cord Injury Care System (MRSCICS) at Shirley Ryan AbilityLab is a leading center for innovative, integrated, interdisciplinary research and care for persons with SCI and is one of the original five NIDILRR-designated Model System Spinal Cord Injury Centers (in partnership with Northwestern University and Northwestern Memorial Hospital).

Midwest Regional Spinal Cord Injury Care System (MRSCICS)

Evaluating the Utility of Spasticity and Brain-Derived Neurotrophic Factor (BDNF) in Pre-dicting Neurologic and Motor Functional Recovery after SCI

Research Project

"I Was A Wheelchair Kid": Real life stories told by adults who were paralyzed as children or teens.

Research Project

Improving Adherence to Exercise Guidelines Using Smartphone-Based Technology and E-coaching: A Proof-of-Concept SMART-Design Study

Research Project

Characterizing the Experience of Spasticity after Spinal Cord Injury

PROJECT TYPE: Spinal Cord Injury, Outcomes

Research Project

Spinal Cord Injury Model Systems Equity and Quality in Assistive Technology (EQuATe) 2.0 Module

PROJECT TYPE: Outcomes

Research Project

MRSCICS Matters Newsletter

Research Project

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Selected Publications

Multisite Hebbian Plasticity Restores Function in Humans with Spinal Cord Injury

OBJECTIVE: Spinal cord injury (SCI) damages synaptic connections between corticospinal axons and motoneurons of many muscles, resulting in devastating paralysis. We hypothesized that strengthening corticospinal-motoneuronal synapses at multiple spinal cord levels through Hebbian plasticity (i.e., "neurons that fire together, wire together") promotes recovery of leg and arm function. METHODS: Twenty participants with chronic SCI were randomly assigned to receive 20-sessions of Hebbian or sham…

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