Translational Cell Therapy Lab
Meet Mitra Lavasani, PhD
Video: The Future of Osteoarthritis
Selected Publications
Systemic Transplantation of Adult Multipotent Stem Cells Functionally Rejuvenates Aged Articular Cartilage.
Osteoarthritis (OA) is the most common and debilitating joint disease of advanced age and has no universally effective therapy. Here, we demonstrate that systemic transplantation of adult multipotent muscle-derived stem/progenitor cells (MDSPCs)-isolated from young mice-rejuvenates the knee articular cartilage (AC) of naturally aged mice. This intervention reduced expression of pro-inflammatory cytokines (Tnf and Il1a) and catabolic matrix-degrading proteinases (Mmp3 and Mmp13) in aged…
read moremTOR signaling plays a critical role in the defects observed in muscle-derived stem/progenitor cells isolated from a murine model of accelerated aging.
read moreBiologic strategies to improve nerve regeneration after peripheral nerve repair.
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Latest Updates
AARP Feature: The New Science of Moving Again After a Stroke
A former Shirley Ryan AbilityLab patient and research participant was recently featured in an AARP article on advances in stroke rehabilitation over the past 25 years. The article highlights how…
view all newsResearcher Studies Nerve Transfer to Restore Diaphragm Function After Spinal Cord Injury
Mackenzie Long, a PhD candidate in Biomedical Engineering at Northwestern University, has been selected as an affiliate trainee in the Pathophysiology and Rehabilitation of Neural Dysfunction (PRND) Training Program.