Translational Cell Therapy Lab
Meet Mitra Lavasani, PhD
Video: The Future of Osteoarthritis
Selected Publications
Systemic Transplantation of Adult Multipotent Stem Cells Functionally Rejuvenates Aged Articular Cartilage.
Osteoarthritis (OA) is the most common and debilitating joint disease of advanced age and has no universally effective therapy. Here, we demonstrate that systemic transplantation of adult multipotent muscle-derived stem/progenitor cells (MDSPCs)-isolated from young mice-rejuvenates the knee articular cartilage (AC) of naturally aged mice. This intervention reduced expression of pro-inflammatory cytokines (Tnf and Il1a) and catabolic matrix-degrading proteinases (Mmp3 and Mmp13) in aged…
read moremTOR signaling plays a critical role in the defects observed in muscle-derived stem/progenitor cells isolated from a murine model of accelerated aging.
read moreBiologic strategies to improve nerve regeneration after peripheral nerve repair.
read moreInterested in joining us?
Latest Updates
Dr. Arun Jayarman featured in Newsweek: AI is giving physical therapy a robotic makeover
"Physical therapy can be critical to recovery, but many patients cannot access it as often as they need due to a growing shortage of therapists and an aging population. Researchers believe AI could help address this challenge by expanding access to rehabilitation." - Newsweek