Translational Cell Therapy Lab
Meet Mitra Lavasani, PhD
Video: The Future of Osteoarthritis
Selected Publications
Systemic Transplantation of Adult Multipotent Stem Cells Functionally Rejuvenates Aged Articular Cartilage.
Osteoarthritis (OA) is the most common and debilitating joint disease of advanced age and has no universally effective therapy. Here, we demonstrate that systemic transplantation of adult multipotent muscle-derived stem/progenitor cells (MDSPCs)-isolated from young mice-rejuvenates the knee articular cartilage (AC) of naturally aged mice. This intervention reduced expression of pro-inflammatory cytokines (Tnf and Il1a) and catabolic matrix-degrading proteinases (Mmp3 and Mmp13) in aged…
read moremTOR signaling plays a critical role in the defects observed in muscle-derived stem/progenitor cells isolated from a murine model of accelerated aging.
read moreBiologic strategies to improve nerve regeneration after peripheral nerve repair.
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Latest Updates
25 Years & Going Strong: Celebrating the Center for Aphasia Research & Treatment
For the past quarter century, Shirley Ryan AbilityLab's Center for Aphasia Research & Treatment has been a lifeline. Through clinical treatment, research, extensive programming and outreach,…
view all newsMeasuring Brain Activity of Patients With Aphasia During Therapy
Researchers at the Center for Aphasia Research & Treatment at Shirley Ryan AbilityLab hope to find new ways to personalize treatment and improve outcomes for people with aphasia — using a non-invasive neuroimaging technique to discover how the brain responds during therapy.
Aphasia Research SLPs Stacy Chrzastowski & Abby Jeppson Complete Northwestern Clinical Bioethics Scholars Program
Stacy Chrzastowski and Abby Jeppson — two research speech-language pathologists in the Center for Aphasia Research & Treatment — recently graduated from the Northwestern Clinical Bioethics Scholars Program.