Collagen Cables

Project

Skeletal Muscle Design in Animals and People

Body

The purpose of skeletal muscle is to produce force and, ultimately, movement. As such, this highly specialized tissue has been studied extensively by bioengineers.

Skeletal muscle can be affected to varying levels of severity across a wide range of diagnoses. For example, spasticity can be appreciated following a stroke, spinal cord injury, or in perinatal brain injuries. This, as well as other skeletal muscle disease processes and disorders, can influence an individual's independence and participation in home, school, and community environments. 

But, without understanding of typical skeletal muscle architecture, we cannot begin to implement effective treatments. Thus, through application of basic science principles, we are able to learn about normal skeletal muscle design and subsequently develop solutions for management within a compromised system.

Collagen fibrils are organized into cables in skeletal muscle ECMFigure One Caption

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Spasticity

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