Dr. Colin Franz, MD/PhD, is a physician and scientist at the Shirley Ryan AbilityLab. His subspecialties include neuromuscular medicine, electrodiagnostic medicine, and neuromuscular ultrasound. He see patients for (i) peripheral nerve injuries, (ii) brachial plexus injuries, (iii) nerve or tendon transfer candidates or postoperative rehabilitation, (iv) polyneuropathy, diaphragm muscle weakness and ultrasound studies, and (v) motor neuron diseases such as ALS. He is the director of the Electromyography (clinical) and Regenerative Neurorehabilitation (research) laboratories at the Shirley Ryan AbilityLab hospital.
His research is heavily inspired by the patient populations he cares for. His laboratory team takes a highly technology-oriented approach to precision rehabilitation medicine. Current studies range from transient (resorbable) implanted devices to deliver therapeutics directly to regenerating axons, to making human neurons derived from patient-derived pluripotent stem cells to determine isolate how individual genetic factors effect neurotrauma outcomes. Via many strong collaborations in Chicago and across North America, his lab is able to address clinical problems in neurorehabilitation, neurotrauma, nerve regeneration and degeneration. His research is supported by the NIH, Craig H. Nielsen Foundation, Foundation for Physical Medicine and Rehabilitation, as well as private gifts from community members such as the Belle Carnell (in memoriam) Regeneration Neurorehabilitation Fund.
Shirley Ryan AbilityLab
355 East Erie
Chicago, IL 60611
Education & Training
Honors & Awards
Foundation for PM&R - Richard S. Materson ERF New Investigator Research Award"Neurotrauma in a Dish" - An induced pluripotent stem cell-based assay to determine patient specific factors affecting rehabilitation outcomes, 2018
Helen Cooper Resident, Rehabilitation Institute of ChicagoRecognition of the physical medicine and rehabilitation resident who made the greatest contribution to teaching., 2016
Lydia Sikora Memorial Award, University of CalgaryRecognition of the medical student who made the most outstanding contribution to research., 2011
Society for NeuroscienceMember, 2003
Peripheral Nerve SocietyMember, 2011
American Academy of Physical Medicine and RehabilitationMember, 2012
American Association of Neuromuscular & Electrodiagnostic MedicineMember and Research Committee, 2017
This lab uses a combination of molecular, biochemical, and electrophysiological assays to study axon regeneration and motor neuron disease with a priority on human preclinical models such as iPSC-neurons.view lab