Levi Hargrove, PhD

Levi Hargrove, PhD

Vice President, Strategic Research Infrastructure
Scientific Chair, The Regenstein Center for Bionic Medicine

My Lab

Neural Engineering for Prosthetics & Orthotics Lab

Our research focuses on developing neural control systems for upper and lower prosthetics.

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@LeviHargrove

About Me

Levi Hargrove, PhD, is an internationally recognized leader in the development of pattern recognition-based control systems for prosthetic limbs. 

At Shirley Ryan AbilityLab, Dr. Hargrove serves as vice president, strategic research infrastructure. In this role, he is responsible for advancing the organization’s research enterprise by further strengthening research infrastructure, guiding high-priority initiatives and helping accelerate the translation of scientific discoveries into clinical and commercial impact.

Additionally, Dr. Hargrove leads The Regenstein Center for Bionic Medicine — a translational research group that focuses on improving prosthetic options for people with upper- and lower-limb amputations.

Among Dr. Hargrove’s most notable achievements is the development of a groundbreaking bionic arm control system that was commercialized through a startup he co-founded, expanding access to advanced technology for patients worldwide. Additionally, his research resulted in the first “thought-controlled” bionic leg, which uses electromyographic (EMG) signals from the user’s residual leg muscles, combined with mechanical sensor data from the prosthesis, to provide intuitive control of a powered device. Today, he is advancing the field further through a first-of-its-kind, NIH-supported bionic arm osseointegration study.

Since joining Shirley Ryan AbilityLab in 2008, Dr. Hargrove has attracted more than $60 million in grant funding from federal, military and philanthropic sources. Today, the Center for Bionic Medicine is one of the nation's most successful rehabilitation research programs, with a current active portfolio of more than $30 million. Dr. Hargrove's contributions to science have resulted in more than 125 peer-reviewed publications in leading journals, including JAMA, the New England Journal of Medicine, Science Robotics and Nature Biomedical Engineering, as well as multiple patented technologies that have been commercialized and cleared by the FDA.

In 2022, he was inducted into the American Institute for Medical and Biomedical Engineering’s (AIMBE) College of Fellows, a prestigious honor that recognizes the top 2 percent of medical and biological engineers in the country. In 2018, Dr. Hargrove received the American Academy of Orthotists and Prosthetists Research Award — intended to recognize the most outstanding research in the field. In 2014, Dr. Hargrove’s team was awarded the Department of Defense Military Health System Research Symposium Outstanding Research Team/Academia-Industry. 

He is member of the IEEE, the world’s largest technical professional organization dedicated to advancing technology for the benefit of humanity, and was previously an associate editor of IEEE Transactions on Biomedical Engineering and IEEE Transactions on Medical Robotics and Bionics.

 In addition to his work at Shirley Ryan AbilityLab, Dr. Hargrove is also a professor of Physical Medicine & Rehabilitation and Biomedical Engineering at Northwestern University. He earned a Bachelor of Science in Electrical Engineering (BScE), Master of Science in Electrical Engineering (MScE) and Doctor of Philosophy (PhD) in Electrical Engineering from the University of New Brunswick in Canada. 

Location

Shirley Ryan AbilityLab

355 East Erie

Chicago, IL 60611

Education & Training

  • Education

    1998 – 2003

    Electrical Engineering, University of New Brunswick

    2003 – 2005

    Electrical Engineering, University of New Brunswick

    2005 – 2008

    Electrical Engineering, University of New Brunswick

Recent Publications

Modeling Expected Reaching Error and Behaviors for Motor Adaptation.
Earley EJ, Hargrove LJ
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
doi: 10.1109/EMBC.2019.8857562
A Survey of Teleceptive Sensing for Wearable Assistive Robotic Devices.
Krausz NE, Hargrove LJ
Sensors (Basel, Switzerland)
doi: 10.3390/s19235238
Determining User Intent of Partly Dynamic Shoulder Tasks in Individuals With Chronic Stroke Using Pattern Recognition.
Kopke JV, Ellis MD, Hargrove LJ
IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
doi: 10.1109/TNSRE.2019.2955029

Honors & Awards

  • Young Professional Award
    Association of Professional Engineerings and Geoscientists of New Brunwick, 2014
  • MHSRS Team Award for Outstanding Research Accomplishment
    United States Army, 2015
  • Collaboration Award
    Chicago Innovation Awards, 2015
  • Research Award
    American Academy of Orthotists & Prosthetists, 2018

Selected Patents

  • Ambulation Prediction Controller for Assistive Device
    9,443,203 B2
    Rehabilitation Institute of Chicago, 2016
  • Systems and Methods of Myoelectric Prosthesis Control
    13/587,755
    Rehabilitation Institute of Chicago, 2014
  • Autoconfiguration of Pattern-Recognition Controlled Myoelectric Prostheses
    61/675,147
    Rehabilitation Institute of Chicago, 2014

Professional Affiliations

  • Professional Engineer
    Association of Professional Engineers and Geoscientists of New Brunswick, 2008
  • Member
    IEEE, 2001
  • Member
    International Society of Electrophysiology and Kinesiology, 2011

Research Interests

  • Control of Bionic Limbs
  • Biological Signal Processing
  • Pattern Recognition

Current Grant Support

  • National Institutes of Health R01
    Intuitive Control of a Hybrid Prosthetic Leg During Ambulation. Role: Principal Investigator, 2018 - 2023
  • National Institutes of Health R01
    The Functional Importance of Powered Wrist Flexion for Upper Limb Prostheses. Role: Principal Investigator, 2018 - 2023
  • NIDILRR
    Technologies to Evaluate and Advance Manipulation and Mobility. Role: Co-Investigator, 2018 - 2023
  • Department of Defense
    The Functional Importance of Powered Wrist Flexion. Role: Co-Investigator, 2019 - 2023
  • Department of Defense
    Flexible Epidermal Electrodes for Intuitive Control of Powered Arm and Leg Prostheses, 2018 - 2021
  • Department of Defense
    Determining the Functional Importance of a Powered Multifunction Wrist. Role: Principal Investigator, 2017 - 2020
  • Department of Defenese
    Motorized Hip Orthoses to Improve the Gait Ability of Transfemoral Amputees. Role: Co-Investigator, 2017 - 2020
  • Department of Defense
    Development and Validation of a Self-Adapting Myoelectrically Controlled Prosthetic Ankle with Continuously Variable Stiffness, 2017 - 2020