Our Clinical Trials
We are recruiting participants for all of our studies.
Closed loop control of vibration for muscle spasms after human spinal cord injury: efficacy and mechanism
This study will study and hope to understand and reduce the muscle spasms that that can sometimes occur post injury in spinal cord patients.read more
Vibration attenuates spasm-like activity in humans with spinal cord injury.
KEY POINTS: Cutaneous reflexes were tested to examine the neuronal mechanisms contributing to muscle spasms in humans with chronic spinal cord injury (SCI). Specifically, we tested the effect of Achilles and tibialis anterior tendon vibration on the early and late components of the cutaneous reflex and reciprocal Ia inhibition in the soleus and tibialis anterior muscles in humans with chronic SCI. We found that tendon vibration reduced the amplitude of later but not earlier cutaneous reflex…read more
Cortical and Subcortical Effects of Transcutaneous Spinal Cord Stimulation in Humans with Tetraplegia.read more
Changes in Motoneuron Excitability during Voluntary Muscle Activity in Humans with Spinal Cord Injury.read more
Interested in joining us?
Currently AbbVie is partnering with the Max Näder Center for Rehabilitation Technologies and Outcomes Research of the Shirley Ryan AbilityLab, a global leader in physical medicine and rehabilitation, and MC10, a health digital solutions company, in a pilot study involving 20 spinal cord injury patients. The pilot study will inform the ongoing Phase 2 study of elezanumab by testing optimal biosensor placement to capture surface electromyography (sEMG), among other assessments.