Generic Background Image
  1. Research
  2. Labs
  3. Max Näder RT&O
  4. Projects
  5. The BO2ST Trial

Breathing low oxygen to enhance spinal stimulation training and functional recovery in persons with chronic spinal cord injury: The BO2ST Trial

Request an appointment

Overview

The goal of this double-blind, placebo-controlled, block-randomized clinical trial is to investigate the efficacy and potency of daily acute intermittent hypoxia (AIH) combined with transcutaneous electrical spinal stimulation (tSTIM) and skill-based walking practice. We hypothesize that the combination of AIH, tSTIM, and walking practice will boost the efficacy of training-related gains without triggering maladaptive changes.

Subject Population

  • Age 18 to 70 years
  • Ambulatory incomplete Spinal Cord Injury C2-L2
  • ASIA C or D

Study Personnel

Arun Jayaraman, PhD, PT

Arun Jayaraman, PT, PhD

Executive Director, Technology & Innovation Hub (tiHUB); Director, Max Näder Center for Rehabilitation Technologies & Outcomes Research

mentioned in this article

Study Partners

This study is in collaboration with the Inspire Lab led by Dr. Randy Trumbower at Spaulding Rehabilitation Hospital.

Funding Source

Department of Defense

Let's get connected.

Request an appointment